INTER-KINGDOM SIGNALING BY THE LEGIONELLA QUORUM SENSING MOLECULE LAI-1 MODULATES CELL MIGRATION THROUGH AN IQGAP1-CDC42-ARHGEF9-DEPENDENT PATHWAY.

Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway.

Small molecule signaling promotes the communication between bacteria as well as between bacteria and eukaryotes.The opportunistic pathogenic bacterium Legionella pneumophila employs LAI-1 (3-hydroxypentadecane-4-one) for bacterial cell-cell communication.LAI-1 is produced and detected by the Lqs (Legionella quorum sensing) system, which regulates a

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Policy and behavioral response to shock events: An agent-based model of the effectiveness and equity of policy design features.

In the aftermath of shock events, policy responses tend to be crafted under significant time constraints and high levels of uncertainty.The extent to which individuals comply with different policy designs can further influence how effective the policy responses are and WOMENS TOPS how equitably their impacts are distributed in the population.Tools

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